Your Guide To Why BPC-157 & TB-500 Peptides Work Better Together


Definition of BPC-157

Short chains of amino acids are known as synthetic peptides. BPC-157 falls under this category. One of the proteins in BPC-157 is responsible for protecting the body and is present inside the digestive tract. Many people believe that since BPC-157 is “naturally located in our stomach and hence money cannot be made on it,” it is not being investigated extensively. This affirmation is just not true. According to the patents, BPC-157 is a synthetic polypeptide.

BPC-157’s Scientific Background

BPC-157, a synthetic peptide, has received minimal attention in the scientific literature. In my most recent search, single human research with minimal information on rectally given BPC-157 for ulcerative colitis was found, which was conducted many months ago. Even though it began in 2015 and was expected to be completed in 2016, a second registered clinical study remained unpublished. In several studies, only in rats has BPC-157 been demonstrated to enhance healing time for skeletal muscle, ligaments, and tendons.


What does TB-500 stand for?

There are 43 amino acids in the human protein thymosin beta-4 (TB-500). Many tissues contain TB-500, which has been found to aid tissue restoration and cell proliferation.

What Is TB-500’s Scientific Basis?

TB-500 has been found in animal and cell culture studies to reduce pro-inflammatory cytokines and aid in developing stem cells. It is critical in the recovery and regeneration of tissues that have been injured. In Phase II clinical studies, pressure ulcers, stasis ulcers, and the skin disorder epidermolysis bullous (EB) were all demonstrated to heal more quickly with TB-500. TB-500 has been shown to have favorable benefits in several Phase I and Phase II clinical studies for wound healing, dry eyes to heart failure.

TB-500 and thymosin beta-4 were successful in Phase I and Phase II clinical studies; however, a search only finds finished or discontinued trials, with no current ongoing research.

What’s the difference between them?

Both TB 500 and BPC 157 have excellent healing and recovery properties in animals. Each peptide enhances recovery from joint, bone, muscle, and connective tissue injuries. While simultaneously fostering increased joint, tendon, and ligament flexibility and strength, they also work to protect the musculoskeletal system from damage. Some fundamental distinctions exist in their origin and structure, administration, and the kinds of tissue they most strongly influence.

The administration is a significant distinction between the two substances (how the product is given to the animal). Most patients get TB-500 in doses of 10 to 20 mg once or twice weekly.

A daily dose of up to 1000mcg (1 mg) of BPC-157 is prescribed for patients with Parkinson’s disease. Because of this, the weekly doses are much lower, ranging from 1.75mg to 7mg. Additionally, TB-500 has a systemic impact, which means it stimulates healing in wounded tissue throughout the animal’s body, regardless of where it is administered. TB-500’s systemic effect may be more critical than its local effect.

On the contrary, BPC-157 has a local healing effect. This effect implies that it is most effective near where it is administered. The gastrointestinal and nervous systems have also been proven to benefit significantly from BPC-157’s remarkable healing and protecting properties. Consequently, even when considering its localized healing benefits, it helps encourage recovery and prevent injury in these regions when administered orally. Oral BPC-157 is a topic worth exploring in depth.

What you need to know about BPC 157 and TB-500 together

BPC 157 & TB 500 blend significantly outperformed BPC-157 alone. As a consequence, I cannot make a direct comparison between the first and second treatments with BPC-157. As a result, two confounding factors are hard to quantify.

1) How effective was the second treatment with BPC-157 and TB-500 after the first round of BPC-157 was administered?

2) It’s hard to say how well the standalone version of the TB-500 would have performed.